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1

Synthesis of Tetrodotoxin, a Classic but Still Fascinating Natural Product

Nishikawa, Toshio, Isobe, Minoru

Journal:

The Chemical Record

Year:

2013

Language:

english

File:

PDF, 1.60 MB

english, 2013

2

An Efficient Total Synthesis of Optically Active Tetrodotoxin

Toshio Nishikawa, Daisuke Urabe, Minoru Isobe

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

3

ChemInform Abstract: Hydrosilylation of Acetylenes with Catalytic Biscobalthexacarbonyl Complex and Its Application to Heteroconjugate Addition Methodology.

Minoru Isobe, Rena Nishizawa, Toshio Nishikawa, Kenji Yoza

Journal:

Year:

1999

File:

PDF, 31 KB

1999

4

Interactions between verapamil and metoprolol in the developing chick embryo heart

Toshio Nishikawa, Takeshi Kasajima, Takao Kanai

Journal:

Journal of Applied Toxicology

Year:

1991

Language:

english

File:

PDF, 350 KB

english, 1991

5

Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation

Minoru Isobe, Yoshio Fukuda, Toshio Nishikawa, Philippe Chabert, Takatoshi Kawai, Toshio Goto

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 247 KB

english, 1990

6

Hydrosilylation of acetylenes with catalytic biscobalthexacarbonyl complex and its application to heteroconjugate addition methodology

Minoru Isobe, Rena Nishizawa, Toshio Nishikawa, Kenji Yoza

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 289 KB

english, 1999

7

Genotoxicity of nano/microparticles inin vitromicronuclei,in vivocomet and mutation assay systems

Yukari Totsuka, Takashi Higuchi, Toshio Imai, Akiyoshi Nishikawa, Takehiko Nohmi, Tatsuya Kato, Shuich Masuda, Naohide Kinae, Kyoko Hiyoshi, Sayaka Ogo, Masanobu Kawanishi, Takashi Yagi, Takamichi Ich

Journal:

Particle and Fibre Toxicology

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

8

Ca2+ -calmodulin-dependent phosphorylation and platelet secretion

Nishikawa, Masakatsu, Tanaka, Toshio, Hidaka, Hiroyoshi

Journal:

Year:

1980

File:

PDF, 439 KB

1980

9

Swimming exercise in infancy has beneficial effect on the hearts in cardiomyopathic Syrian hamsters

Mariko Tatsuguchi, Eriko Hiratsuka, Shuichi Machida, Toshio Nishikawa, Shin-Ichiro Imamura, Satoru Shimizu, Masahiko Nishimura, Issei Komuro, Yoshiyuki Furutani, Michiko Furutani, Hiroaki Nagao, Keiko

Journal:

Journal of Muscle Research and Cell Motility

Year:

2004

Language:

english

File:

PDF, 256 KB

english, 2004

10

Two-generation reproductive toxicity study of aluminium sulfate in rats

Mutsuko Hirata-Koizumi, Sakiko Fujii, Atsushi Ono, Akihiko Hirose, Toshio Imai, Kumiko Ogawa, Makoto Ema, Akiyoshi Nishikawa

Journal:

Reproductive Toxicology

Year:

2011

Language:

english

File:

PDF, 515 KB

english, 2011

11

First Asymmetric Total Synthesis of Tetrodotoxin

Ohyabu, Norio, Nishikawa, Toshio, Isobe, Minoru

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

12

Prognostic factors of acute cholangitis in cases managed using the Tokyo Guidelines

Toshio Tsuyuguchi, Harutoshi Sugiyama, Yuji Sakai, Takao Nishikawa, Osamu Yokosuka, Toshihiko Mayumi, Seiki Kiriyama, Masamichi Yokoe, Tadahiro Takada

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

2012

Language:

english

File:

PDF, 442 KB

english, 2012

13

Turtles have evolved perfectly self-righting shells

Toshio, Nishikawa, Takeshi, Kasajima, Takao, Kanai

Journal:

Year:

2007

Language:

english

File:

PDF, 104 KB

english, 2007

14

[IEEE 19th European Microwave Conference, 1989 - London, UK (1989.10.4-1989.10.6)] 19th European Microwave Conference, 1989 - 4GHz Band Band-Pass Filter using an Orthogonal Array Coupling TM110 Dual Mode Dielectric Resonator

Nishikawa, Toshio, Ishikawa, Youhei, Hattori, Jun, Wakino, Kikuo, Kobayashi, Yoshio

Year:

1989

Language:

english

File:

PDF, 4.48 MB

english, 1989

15

A New Deprotection Procedure of MTM Ether

Adachi, Masaatsu, Hashimoto, Honoka, Sakakibara, Ryo, Imazu, Takuya, Nishikawa, Toshio

Journal:

Year:

2014

Language:

english

File:

PDF, 208 KB

english, 2014

16

Stereoelectronic and Steric Effects for Critical Oxidation to the Cyclohexane Derivatives for an Intermediate to (-)-Tetrodotoxin

Bamba, Makoto, Nishikawa, Toshio, Isobe, Minoru

Journal:

Year:

1998

Language:

english

File:

PDF, 39 KB

english, 1998

17

Synthesis of Bicyclic Hydroxy Lactone Intermediates toward (-)-Tetrodotoxin

Yamamoto, Noboru, Nishikawa, Toshio, Isobe, Minoru

Journal:

Year:

1995

File:

PDF, 152 KB

1995

18

Synthesis of an Advanced Intermediate Bearing Two Hydroxy Groups for (−)-Tetrodotoxin and Its Analogs

Nishikawa, Toshio, Koide, Yuya, Adachi, Masaatsu, Isobe, Minoru

Journal:

Bulletin of the Chemical Society of Japan

Year:

2010

Language:

english

File:

PDF, 115 KB

english, 2010

19

Synthetic studies on a stereochemically complex natural product: designs for the total synthesis of (-)-tetrodotoxin

Isobe, M., Nishikawa, T., Fukami, Naoki, Goto, Toshio

Journal:

Pure & Applied Chemistry

Year:

1987

Language:

english

File:

PDF, 233 KB

english, 1987

20

Comparison of the Clinical Presentation, Treatment, and Outcome of Fulminant and Acute Myocarditis in Children

Saji, Tsutomu, Matsuura, Hiroyuki, Hasegawa, Kei, Nishikawa, Toshio, Yamamoto, Eiichi, Ohki, Hirotaka, Yasukochi, Satoshi, Arakaki, Yoshio, Joo, Kunio, Nakazawa, Makoto

Journal:

Circulation Journal

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

21

Age-associated myocardial changes in various heart diseases. A clinicopathologic analysis in biopsied and autopsied myocardium.

SEKIGUCHI, Morie, NISHINO, Hiroshi, NISHIKAWA, Toshio, MORIMOTO, Shinichiro, HIROE, Michiaki

Journal:

Japanese Circulation Journal

Year:

1986

File:

PDF, 1.85 MB

1986

22

Influence of Impact Load on Fatigue Bending Strength of Case-Hardened Gears

AIDA, Toshio, FUJIO, Hiroshige, NISHIKAWA, Mikio, HIGASHI, Ryuji

Journal:

Bulletin of JSME

Year:

1972

File:

PDF, 736 KB

1972

23

Preparation of Ceramic Surfaces for Microscopic Observation by Penning Discharge Microetching.

NISHIKAWA, Eiichi, SUGITA, Toshio, TAKAHASHI, Toshiyuki, IDA, Hitoshi, TSUYA, Yuuko

Journal:

Journal of the Ceramic Society of Japan

Year:

2000

Language:

english

File:

PDF, 4.50 MB

english, 2000

24

Design of gearshift lever characteristics based on human arm mechanical properties

NISHIKAWA, Kazuo, FURUKAWA, Kouji, KAWATE, Isao, NOUZAWA, Takahide, TSUJI, Toshio

Journal:

Transactions of the JSME (in Japanese)

Year:

2014

File:

PDF, 1.00 MB

2014

25

Diffusion of a Multi-Ion Species Plasma Due to Drift Wave Fluctuations

Tange, Toshio, Itoh, Kimitaka, Inoue, Sanae, Nishikawa, Kyoji

Journal:

Journal of the Physical Society of Japan

Year:

1977

File:

PDF, 1.06 MB

1977

26

The First Asymmetric Total Synthesis of Tetrodotoxin, a Puffer Fish Toxin

Isobe, Minoru, Ohyabu, Norio, Nishikawa, Toshio

Journal:

Journal of Synthetic Organic Chemistry Japan

Year:

2007

Language:

english

File:

PDF, 1.48 MB

english, 2007

27

Stereoselektive Synthese von (−)-5,11-Didesoxytetrodotoxin

Toshio Nishikawa, Masanori Asai, Norio Ohyabu, Noboru Yamamoto, Minoru Isobe

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 93 KB

german, 1999

28

Stereocontrolled Synthesis of (−)-5,11-Dideoxytetrodotoxin

Toshio Nishikawa, Masanori Asai, Norio Ohyabu, Noboru Yamamoto, Minoru Isobe

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

29

Successful treatment of refractory anemia by high-dose methylprednisolone associated with an increment in CD68-positive cells in bone marrow

Sayuri Motomura, Toshiko Motoji, Keiko Okutomi, Toshio Nishikawa, Takeshi Kasajima, Hideaki Mizoguchi

Journal:

American Journal of Hematology

Year:

2001

Language:

english

File:

PDF, 112 KB

english, 2001

30

Histopathologic classification of uterine choriocarcinoma

Yoshiki Nishikawa, Shigeaki Kaseki, Yutaka Tomoda, Takao Ishizuka, Yasumasa Asai, Toshio Suzuki, Hiroshi Ushijima

Journal:

Year:

1985

Language:

english

File:

PDF, 3.25 MB

english, 1985

31

Decreased serum aldolase B levels in patients with malignant tumors

Masahiro Asaka, Toshio Kimura, Shuhji Nishikawa, Tomotsu Miyazuki, Elliot Alpert

Journal:

Year:

1988

Language:

english

File:

PDF, 399 KB

english, 1988

32

Activated human T cells directly induce osteoclastogenesis from human monocytes: Possible role of T cells in bone destruction in rheumatoid arthritis patients

Shigeru Kotake, Nobuyuki Udagawa, Masayuki Hakoda, Makio Mogi, Kazuki Yano, Eisuke Tsuda, Ken Takahashi, Takefumi Furuya, Shigeru Ishiyama, Kang-Jung Kim, Seiji Saito, Toshio Nishikawa, Naoyuki Takaha

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 8.59 MB

english, 2001

33

An Efficient Total Synthesis of Optically Active Tetrodotoxin

Toshio Nishikawa, Daisuke Urabe, Minoru Isobe

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

34

A Synthetic Route to the Saxitoxin Skeleton: Synthesis of Decarbamoyl α-Saxitoxinol, an Analogue of Saxitoxin Produced by the Cyanobacterium Lyngbya wollei

Dr. Yusuke Sawayama, Prof. Toshio Nishikawa

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

35

A Synthetic Route to the Saxitoxin Skeleton: Synthesis of Decarbamoyl α-Saxitoxinol, an Analogue of Saxitoxin Produced by the Cyanobacterium Lyngbya wollei

Dr. Yusuke Sawayama, Prof. Toshio Nishikawa

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

36

Enhancement of antibody production by growth factor addition in perfusion and hollow-fiber culture systems

Takeshi Omasa, Masaki Kobayashi, Toshio Nishikawa, Suteaki Shioya, Ken-ichi Suga, Syo-ichi Uemura, Yasuo Kitani, Yoshio Imamura

Journal:

Biotechnology and Bioengineering

Year:

1995

Language:

english

File:

PDF, 655 KB

english, 1995

37

Dehydrocoelenterazine is the Organic Substance Constituting the Prosthetic Group of Pholasin

Eiko Tanaka, Masaki Kuse, Toshio Nishikawa

Journal:

Year:

2009

Language:

english

File:

PDF, 239 KB

english, 2009

38

Stereocontrolled Synthesis of 8,11-Dideoxytetrodotoxin, An Unnatural Analogue of Puffer Fish Toxin

Toshio Nishikawa, Daisuke Urabe, Kazumasa Yoshida, Tomoko Iwabuchi, Masanori Asai, Minoru Isobe

Journal:

Chemistry - A European Journal

Year:

2004

Language:

english

File:

PDF, 288 KB

english, 2004

39

ChemInform Abstract: Stereocontrolled Synthesis and Reactivity of Sugar Acetylenes

Minoru Isobe, Rena Nishizawa, Seijiro Hosokawa, Toshio Nishikawa

Journal:

Year:

1999

File:

PDF, 24 KB

1999

40

ChemInform Abstract: Synthesis of a α-C-Mannosyltryptophan Derivative, Naturally Occurring C-Glycosyl Amino Acid Found in Human Ribonuclease.

Toshio Nishikawa, Miyuki Ishikawa, Minoru Isobe

Journal:

Year:

1999

File:

PDF, 33 KB

1999

41

ChemInform Abstract: Electronic Factors in the C-Glycosidation with Silylacetylene.

Minoru Isobe, Rungnapha Saeeng, Rena Nishizawa, Masato Konobe, Toshio Nishikawa

Journal:

Year:

1999

File:

PDF, 30 KB

1999

42

ChemInform Abstract: Stereocontrolled Synthesis of (-)-5,11-Dideoxytetrodotoxin.

Masanori Asai, Toshio Nishikawa, Norio Ohyabu, Noboru Yamamoto, Minoru Isobe

Journal:

Year:

2001

File:

PDF, 26 KB

2001

43

ChemInform Abstract: Total Synthesis of α-C-Mannosyltryptophan, a Naturally Occurring C-Glycosyl Amino Acid.

Toshio Nishikawa, Miyuki Ishikawa, Kyoko Wada, Minoru Isobe

Journal:

Year:

2001

File:

PDF, 31 KB

2001

44

Scandium Perchlorate as a Superior Lewis Acid for Regioselective Ring Opening of Aziridine Carboxylate with Indoles.

Toshio Nishikawa, Shigeo Kajii, Kyoko Wada, Miyuki Ishikawa, Minoru Isobe

Journal:

Year:

2002

File:

PDF, 29 KB

2002

45

Total Syntheses of 11-Deoxytetrodotoxin and 8,11- Dideoxytetrodotoxin

Toshio Nishikawa, Daisuke Urabe, Kazumasa Yoshida, Tomoko Iwabuchi, Masanori Asai, Minoru Isobe

Journal:

Year:

2003

File:

PDF, 52 KB

2003

46

Synthetic Studies on Structurally Novel Bioactive Compounds — Synthetic Studies on Cyclic Enediyne Compounds

Toshio Nishikawa

Journal:

Year:

2004

File:

PDF, 59 KB

2004

47

Synthesis of Model Compound Containing an Indole Spiro-β-lactam Moiety with Vinylchloride in Chartellines.

Toshio Nishikawa, Shigeo Kajii, Minoru Isobe

Journal:

Year:

2004

File:

PDF, 136 KB

2004

48

An Efficient Total Synthesis of Optically Active Tetrodotoxin.

Toshio Nishikawa, Daisuke Urabe, Minoru Isobe

Journal:

Year:

2005

File:

PDF, 11 KB

2005

49

A Novel Deprotection of Trichloroacetamide.

Daisuke Urabe, Kumi Sugino, Toshio Nishikawa, Minoru Isobe

Journal:

Year:

2005

File:

PDF, 26 KB

2005

50

Synthesis of Functionalized Cyclopentane for Pactamycin (II), a Potent Antitumor Antibiotic.

Takashi Tsujimoto, Toshio Nishikawa, Daisuke Urabe, Minoru Isobe

Journal:

Year:

2005

File:

PDF, 13 KB

2005

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